Acne/Angiofibromas of tuberous sclerosis.

Abstract

Tuberous sclerosis is a phacomatosis, namely an inherited disorder involving the skin and the nervous aystem. Besides the classic forms with typical skin lesions (congenital hypomelanic macules, angiofibromas, Koenen tumors, shagreen patches) and characteristic neurological lesions (seizures), do exist minimal forms, which can present only cutaneous lesions, mainly angiofibromas. In the past, the latter were called sebaceous adenomas, mainly due to their distribution around the nose, which is a region particularly rich in sebaceous glands. In some cases angiofibromas of tuberous sclerosis should be differentiated from inflammatory acne.