Juvenile amyopathic dermatomyositis in two girls.

Abstract

Juvenile amyopathic dermatomyositis (JADM) is a rare disease characterized by typical skin lesions of dermatomyositis, lack of muscle involvement, laboratory and electromyographic alterations. When JADM is accompanied by abnormalities of the nail-fold capillaries, it can non-invasively be diagnosed using a capillary microscope. The Authors report two girls with JADM, whose nail-fold capillaries showed significant changes. After a follow up of 2 years, the disease showed neither progression nor regression leading to introduce chloroquine. The latter induced significant improvement of the skin symptoms and sign and also of the nail fold capillaroscopy changes.