Lymphomatoid papulosis type C.

Abstract

Lymphomatoid papulosis type C is a recurrent papulo-nodular eruption with histological findings sometimes indistinguishable from CD30+ anaplastic, large cell lymphoma. The main difference between the two disorders is clinical and consists in the fact that lymphomatoid papulosis spontaneously regresses within 4-6 weeks. Another point of contact between the two disorders is that 4% of lymphomatoid papulosis type C turns even after decades to lymphoma (1, 2), more often mycosis fungoides, CD30+, anaplastic, large cell lymphoma and Hodgkin's disease. The persistence of nodular lesions for more than 6 weeks, their progressive enlargement and lymphadenopathy (3) should induce physicians to consider this possible evolution. Prolonged, clinical and ultrasonographic monitoring is thus mandatory.