Onset of epidermolysis bullosa nevus and labial metaplasia following toxic epidermal necrolysis: a case report and review of the literature.

Abstract

Toxic epidermal necrolysis (TEN) is a severe mucocutaneous reaction characterized by widespread epidermal detachment and involvement of multiple mucosal sites. Eruptive melanocytic nevi, including Köbner-type eruptive nevi or epidermolysis bullosa (EB) nevi, have rarely been described as sequelae of TEN, with only a few pediatric cases reported. Labial metaplasia represents an exceptionally rare long-term complication.
We report the case of a 3-year-old female who developed two rare long-term pediatric sequelae of TEN: a Köbner-type eruptive melanocytic nevus and labial metaplasia. Awareness of these entities is critical to prevent unnecessary excisions and to ensure appropriate long-term surveillance.