Lichen spinulosus in a patient with Wilson’s disease.

Authors

  • G. Okan Istanbul Aydin University
  • P. Vural Istanbul University, Istanbul Medical Faculty
  • C. Demirkesen Istanbul Acibadem University,

DOI:

https://doi.org/10.26326/2281-9649.35.3.2790

Keywords:

Wilson’s disease, lichen spinulosus, oxidative stress, beta-carotene, zinc

Abstract

Lichen spinulosus (LS) is a rare dermatosis typically observed in children and young adults with unclear pathogenesis. Wilson's disease (WD) is an autosomal recessive disorder characterized by pathological copper accumulation primarily in the liver, with subsequent effects on the other tissues. Oxidative stress resulting from increased free radical production along with deficiencies in antioxidant defence is believed to play a central role in WD pathogenesis. We report the a 12-year-old girl with WD whose symptoms were managed with beta-carotene and zinc rich supplements.

Author Biographies

G. Okan, Istanbul Aydin University

Department of Dermatology, Professor

P. Vural, Istanbul University, Istanbul Medical Faculty

Department of Biochemistry, Professor

C. Demirkesen, Istanbul Acibadem University,

Department of Pathology, Professor

Published

2025-07-21

How to Cite

Okan, G., Vural, P., & Demirkesen, C. (2025). Lichen spinulosus in a patient with Wilson’s disease. European Journal of Pediatric Dermatology, 35(3), 188–9. https://doi.org/10.26326/2281-9649.35.3.2790

Issue

Section

Letters to the Editor