Fibrous hamartoma of infancy

Abstract

Clinical features. Fibrous hamartoma of infancyis usually an isolated hypodermic nodule (1, 5), often on central location -armpits, nape of the neck,groins and root of limbs- rather than acrolocated (4). Fibrous hamartoma of infancy can spontaneouslyregress and its removal is followed by local relapsein less than 15% of cases (3).
The histological examination (2) shows rather cell-poor fibrous trabeculae, whorls of immaturespindle cells plunged in a mucoid matrix and maturefat tissue.
Some problem of differential diagnosis may arise when the histological examination shows only one component of the tumor. In these cases the presence of only immature cells may lead to diagnose a malignancy, whereas the presence of only mature fat tissue may lead to diagnose lipomaand the presence of only spindle cells may lead to diagnose myoma or neuroma.