Pachyonychia congenita 1/Chronic mucocutaneous candidosis.

Abstract

Pachyonychia congenita 1 (PC1) is an inherited skin disorder due to the mutation of a gene codifying for K6a and K16 keratins. Autosomal dominant chronic mucocutaneous candidosis is due to a primary immune deficiency. Although being very different diseases, the nail involvement in both of them can give rise clinically to diagnosis problems.