Interferon alfa-2a therapy for a child with blue rubber-bleb nevus syndrome.

Abstract

We describe a 1-month-old girl with Blue Rubber-Bleb Nevus Syndrome, a rare condi­tion in which multiple venous malformations in the skin are associated with similar gastrointestinal lesions. She presented severe intestinal bleeding without response to corti­costeroids. She received interferon alfa-2a 3 million U/m² per day for a 6-month-period with a good clinical and laboratory evolution.