Nevoid trichorrhexis invaginata (bamboo hairs).

Abstract

We present a boy with breakage of hair on the vertex and along stripes across the scalp. Scanning electron microscopy of the hairs from these regions showed typical invagina­tions. In addition the boy suffered from atopic eczema. Trichorrhexis invaginata is usually found in patients with ichthyosis linearis circum­flexa and allergie predisposition. This association of symptoms and signs is named Comel-­Netherton's syndrome. It is inherited by an autosomal recessive trait, with a higher pene­trance in females. This case probably represents a spontaneous, postzygotic, somatic mutation, presenting in a nevoid pattern in a boy.